Journal of International Society of Preventive and Community Dentistry

REVIEW ARTICLE
Year
: 2020  |  Volume : 10  |  Issue : 4  |  Page : 379--383

Clinical success of platelet-rich fibrin and mineral trioxide aggregate (MTA) or MTA-like agents in healing of periapical lesion in nonsurgically treated pulpless immature permanent teeth: A systematic review


Sourabh R Joshi1, Aparna U Palekar2, Gowri S Pendyala3, Viddyasagar Mopagar1, Neeta Padmawar1, Pratima Shah1 
1 Department of Pediatric & Preventive Dentistry, Rural Dental College, Pravara Institute of Medical Sciences, Loni, Maharashtra, India
2 Department of Conservative Dentistry and Endodontics, Rural Dental College, Pravara Institute of Medical Sciences, Loni, Maharashtra, India
3 Department of Periodontics, Rural Dental College, Pravara Institute of Medical Sciences, Loni, Maharashtra, India

Correspondence Address:
Dr. Sourabh R Joshi
Department of Pediatric & Preventive Dentistry, Rural Dental College, Pravara Institute of Medical Sciences, Loni, Maharashtra.
India

Background: The chances of extrusion of mineral trioxide aggregate (MTA) are quite high if apical barrier is not present in immature pulpless permanent teeth. Platelet-rich fibrin (PRF) enriched with platelets and growth factors serves to accelerate the wound healing of periapical lesion in immature pulpless permanent teeth and also serves as internal matrix to condense MTA. Aim: The aim of the present study was to comprehensively review the clinical success of MTA+PRF in healing of periapical lesions in immature pulpless permanent teeth. Materials and Methods: An electronic search for systematic review was conducted in Pubmed/Medline (www.ncbi.nlm.nih.gov), Cochrane (www.cochrane.org), Scopus (www.scopus.com) databases upto 15th January 2020 related to the healing of periapical lesions in permanent teeth with immature apices when combination of MTA+PRF was used. A sample of 10 relevant studies and case reports were identified in our search out of 65. The sampling method was simple random technique. The studies and case reports with Randomised Controlled Trials(RCTs), Invitro studies, Case reports and animal studies in healing of periapical lesion were included in our comprehensive systematic review. Results: The search showed that the combination of MTA+PRF showed faster and definite periapical lesion healing in immature permanent teeth. The follow-up period was also recorded in all the relevant studies and case reports. Conclusion: Acclerated bone filling was seen in healing of periapical leions when MTA+PRF was used.


How to cite this article:
Joshi SR, Palekar AU, Pendyala GS, Mopagar V, Padmawar N, Shah P. Clinical success of platelet-rich fibrin and mineral trioxide aggregate (MTA) or MTA-like agents in healing of periapical lesion in nonsurgically treated pulpless immature permanent teeth: A systematic review.J Int Soc Prevent Communit Dent 2020;10:379-383


How to cite this URL:
Joshi SR, Palekar AU, Pendyala GS, Mopagar V, Padmawar N, Shah P. Clinical success of platelet-rich fibrin and mineral trioxide aggregate (MTA) or MTA-like agents in healing of periapical lesion in nonsurgically treated pulpless immature permanent teeth: A systematic review. J Int Soc Prevent Communit Dent [serial online] 2020 [cited 2020 Sep 26 ];10:379-383
Available from: http://www.jispcd.org/article.asp?issn=2231-0762;year=2020;volume=10;issue=4;spage=379;epage=383;aulast=Joshi;type=0