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ORIGINAL ARTICLE
Year : 2020  |  Volume : 10  |  Issue : 5  |  Page : 579-584

Ethanol extract of Schinus molle L. (molle) and Erythroxylum coca Lam (coca): Antibacterial properties at different concentrations against Streptococcus mutans: An in vitro study


1 Academic Department, Faculty of Dentistry, Universidad Nacional Federico Villarreal, Lima, Peru
2 Department of Rehabilitative Stomatology, Faculty of Dentistry, Universidad Nacional Mayor de San Marcos, Lima, Peru
3 Postgraduate Department, Faculty of Health Sciences, Universidad Científica del Sur, Lima, Peru

Correspondence Address:
Dr. Frank Mayta-Tovalino
Postgraduate of Health Sciences, Universidad Cientifica del Sur, Av. Paseo de la República 5544, Miraflores
Peru
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jispcd.JISPCD_237_20

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Objective: The aim of this study was to compare in vitro the antibacterial activity of an ethanol extract of Erythroxylum coca Lam (EEE) and Schinus molle L. (EES) at 50% and 75% versus Streptococcus mutans ATCC 25175. Materials and Methods: This was a prospective, comparative, longitudinal experimental study. The ethanol extract of coca and molle leaves was obtained by the vacuum filtration method at concentrations of 50% and 75% and was compared with a positive control (0.12% chlorhexidine). Streptococcus mutans strains were isolated in a culture medium (Mitis Salivarius Agar) ideal for the growth of bacterial colonies. The antibacterial activity of the ethanol extract was carried out following the Kirby–Bauer disk-diffusion method in Mueller–Hinton agar to measure bacterial sensitivity. A value of P < 0.05 was considered statistically significant. Results: Evaluation of the antibacterial effect of EEE and EES at 24 and 48 h showed that a concentration of 75% for both groups had the highest antimicrobial activity against S. mutans (11.2 ± 0.7 mm; 11.6 ± 0.5 mm and 11.3 ± 0.7 mm; 11.8 ± 0.5 mm, respectively). So, the results have shown that the concentration of EEE and EES of 75% has a greater efficacy than the concentration of 50%, but both concentrations are not as effective as chlorhexidine. Conclusion: EEE and EES at concentrations of 50% and 75% present antibacterial activity against S. mutans ATCC 25175.


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