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ORIGINAL ARTICLE
Year : 2020  |  Volume : 10  |  Issue : 6  |  Page : 743-751

Comparison of regenerative potential of platelet-rich fibrin alone and in combination with bovine bone graft in intraosseous defect by single flap approach: A clinical and radiographic study


Department of Periodontics and Implantology, Manubhai Patel Dental College & Hospital, Vadodara, Gujarat, India

Correspondence Address:
Dr. Bhaumik Thakkar
Department of Periodontics and Implantology, C1/6B, Kumbhnath Society, Near Aavkar Hall, Ghodasar Road, Maninagar, Ahmedabad, Gujarat 380008
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jispcd.JISPCD_200_19

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Aim: To compare the regenerative potential of platelet-rich fibrin alone and in combination with bovine bone graft in intraosseous defect by the single flap approach. Materials and Methods: A total of 32 sites of intrabony defects were selected and were treated with platelet-rich fibrin (PRF) alone or in combination with bovine bone graft. Clinical parameters [Gingival index (GI), probing depth (PD), clinical attachment level (CAL), Gingival recession, and radiographic parameters (defect fill, alveolar crest level, and defect depth)] were recorded at baseline, 3 months, and 6 months. Results: Statistical analysis was done by independent and paired t-test. There were statistically significant changes in GI, PD reduction, CAL gain, defect fill, alveolar crest level changes, and defect depth resolution from baseline, 3 months, and 6 months in both the groups (P < 0.001). On intergroup comparison, Group II showed statistically significant changes in a reduction in pocket depth and defect depth resolution at P < 0.001. Conclusion: PRF in combination with bovine bone graft was more effective in the treatment of intrabony defects.


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